Focus and Scope

Singapore Paediatric Journal, published by Singapore Paediatric Society collaborates with Singapore Medical Association. are dedicated to providing physicians with the best research and important information in the world of medical research and science and to present the information in a format that is understandable and clinically useful. Committed to publishing multidisciplinary research that spans the entire spectrum of healthcare and medicine access, Singapore Paediatric Journal aims at an international audience of pharmacists, clinicians, medical ethicists, regulators, and researchers, providing an online forum for the rapid dissemination of recent research and perspectives in this area.

Singapore Paediatric Journal Evidence seeks to advance clinical trial research and clinical practice by:

• Publishing high-quality studies from the front lines of medical research.
• Challenging the medical community to take new approaches to clinical trial design and execution that yield more powerful clinical evidence.
• Sparking debate and conversation around areas of medicine where clinical decisions are made without sufficient evidence.
• Engaging physicians in a more sophisticated and meaningful way with clinical evidence.

Adhering to the rigorous peer-review and quality standards expected from Singapore Paediatric Journal Evidence publishes:

• Original research, clinical trials, and other clinically grounded work (e.g., epidemiology studies, first-in-human trials, meta-analyses) that validate or challenge prior clinical findings.
• Standard reviews, systematic reviews, and other review types that contextualize research findings with the aim of accelerating clinical adoption of new evidence.
• Case studies and reviews of clinical trial methodology that enhance understanding of trial strengths and weaknesses.
• Curbside consult series that addresses common patient care issues.
• Morning Report series solicited case presentation articles that are delivered in a morning report format.

Generation of Evidence

The process of generating evidence is a key area of focus for Singapore Paediatric Journal Evidence. We encourage readers to evaluate the reasoning behind the complex decisions that investigators make in trial design and execution, and to assess the quality of evidence produced in trials. Our goal is to build a community that takes a rigorous approach to evaluating evidence and assessing its impact on clinical decision-making.

Statistical Methods

Singapore Paediatric Journal Evidence guides readers toward a deeper understanding of the statistical methods used in trials. We provide concise, digestible explanations of research methods to inform the interpretation of the resulting data. In addition, we introduce readers to emerging statistical methods and types of data that will play an increasingly prominent role in future trials.

Multidisciplinary Coverage

Singapore Paediatric Journal Evidence publishes content relevant across all medical disciplines to advance the discussion of how to generate evidence that informs patient care. Physician-scientists, trialists, and general medicine and subspecialty clinicians will all benefit from this publication.

Singapore Paediatric Journal covers themes including, but not limited to:

1. Neonatology and Perinatal Medicine

• Neonatal Intensive Care (NICU):
• Management of prematurity and low birth weight infants.
• Respiratory support: respiratory distress syndrome (RDS), surfactant therapy, mechanical ventilation, and bronchopulmonary dysplasia (BPD).
• Neonatal sepsis, necrotizing enterocolitis (NEC), and intraventricular hemorrhage (IVH).
• Hemodynamic support and management of patent ductus arteriosus (PDA).
• Perinatal Medicine:
• Fetal medicine: fetal diagnosis, therapy, and assessment of well-being.
• Transition from fetal to neonatal life.
• Management in the delivery room and neonatal resuscitation.
• Congenital Anomalies and Genetics:
• Diagnosis and initial management of congenital malformations (e.g., cardiac, gastrointestinal, neurologic).
• Neonatal screening and early diagnosis of genetic and metabolic disorders.
• Neonatal Nutrition and Neurodevelopment:
• Parenteral and enteral nutrition for preterm and sick infants.
• Long-term neurodevelopmental outcomes of high-risk infants.

2. General Pediatrics and Primary Care

• Health Supervision and Preventive Care:
• Well-child visits, growth and development surveillance.
• Immunizations: vaccine efficacy, safety, policy, and management of vaccine-preventable diseases.
• Anticipatory guidance and injury prevention.
• Common Childhood Illnesses:
• Management of acute infectious diseases (e.g., otitis media, pharyngitis, pneumonia, gastroenteritis).
• Nutrition and Feeding:
• Breastfeeding, infant formula, and introduction of solid foods.
• Childhood obesity: prevention and management.
• Micronutrient deficiencies.
• Adolescent Medicine:
• Pubertal development, reproductive health, and contraception.
• Mental health screening and management (depression, anxiety).
• Substance use and risk-taking behaviors.

3. Pediatric Medical Subspecialties

• Pediatric Cardiology:
• Congenital heart disease (CHD): diagnosis, medical management, and post-operative care.
• Acquired heart disease: Kawasaki disease, rheumatic fever, myocarditis.
• Arrhythmias and cardiomyopathies in children.
• Pediatric Pulmonology:
• Asthma, cystic fibrosis, and primary ciliary dyskinesia.
• Chronic lung disease of infancy and childhood sleep disorders.
• Pediatric Gastroenterology, Hepatology & Nutrition:
• Inflammatory bowel disease (IBD), celiac disease, and eosinophilic esophagitis.
• Chronic liver disease, cholestasis, and liver transplantation.
• Feeding disorders and failure to thrive.
• Pediatric Endocrinology:
• Type 1 and Type 2 diabetes mellitus, growth hormone deficiency, and disorders of puberty.
• Congenital hypothyroidism and adrenal hyperplasia.
• Pediatric Nephrology:
• Nephrotic syndrome, glomerulonephritis, and hemolytic uremic syndrome (HUS).
• Congenital anomalies of the kidney and urinary tract (CAKUT) and chronic kidney disease.
• Pediatric Neurology:
• Epilepsy and seizure disorders.
• Cerebral palsy, headaches, neuromuscular disorders (e.g., muscular dystrophy), and neurodevelopmental disabilities.
• Pediatric Hematology and Oncology:
• Anemias, sickle cell disease, thalassemia, and bleeding disorders (hemophilia).
• Childhood cancers: leukemia, lymphoma, brain tumors, neuroblastoma, and Wilms' tumor.
• Pediatric Infectious Diseases:
• Diagnosis and treatment of complex infections, antimicrobial stewardship.
• HIV in children, congenital infections, and emerging infectious diseases.
• Pediatric Rheumatology:
• Juvenile Idiopathic Arthritis (JIA), systemic lupus erythematosus, and pediatric vasculitis.
• Pediatric Allergy and Immunology:
• Food allergy, anaphylaxis, allergic rhinitis, and primary immunodeficiency disorders.
• Pediatric Dermatology:
• Atopic dermatitis, vascular anomalies (hemangiomas), and genetic skin diseases (genodermatoses).
• Genetics and Inborn Errors of Metabolism:
• Diagnosis and management of metabolic crises and long-term care for metabolic disorders.
• Syndromology and clinical genetics.

4. Pediatric Surgical Specialties

• General Pediatric Surgery:
• Surgical correction of congenital anomalies (e.g., diaphragmatic hernia, tracheoesophageal fistula, intestinal atresia).
• Management of appendicitis, pyloric stenosis, intussusception, and Hirschsprung's disease.
• Pediatric Cardiothoracic Surgery, Neurosurgery, Orthopedics, Urology, and Otolaryngology.

5. Developmental, Behavioral, and Psychosocial Pediatrics

• Developmental and Behavioral Pediatrics:
• Autism Spectrum Disorder (ASD), Attention-Deficit/Hyperactivity Disorder (ADHD).
• Learning disabilities and intellectual disability.
• Child and Adolescent Psychiatry:
• Mood disorders, anxiety disorders, and eating disorders.
• Psychopharmacology in children and adolescents.
• Child Abuse and Neglect:
• Medical evaluation, recognition, and management of maltreatment.
• Social Pediatrics:
• Impact of social determinants of health on children.

6. Cross-Cutting Themes and Foundational Topics

• Pediatric Critical Care (PICU):
• Management of critically ill infants and children with multi-organ system failure, sepsis, and post-operative needs.
• Pediatric Emergency Medicine:
• Acute care of pediatric trauma and medical emergencies.
• Pediatric resuscitation and procedural sedation.
• Public Health, Policy, and Advocacy:
• Child health policy, injury prevention, and community pediatrics.
• Global Child Health:
• Major causes of childhood mortality and morbidity in low- and middle-income countries.
• Basic Science and Translational Research:
• Pathophysiology of pediatric diseases, developmental biology, and pediatric pharmacology.
• Ethics in Pediatrics and Neonatology:
• Ethical dilemmas in decision-making, end-of-life care, and genetic testing.
• Education and Simulation in Pediatrics.