Nocturnal Home Hemodialysis: Clinical Outcomes

Abstract

Introduction: Nocturnal home hemodialysis (NHHD) (6–8 hours, 3–6 nights/week) offers potential advantages over conventional in-center dialysis. Methods: Meta-analysis of 15 studies comparing NHHD with conventional hemodialysis for blood pressure, phosphate, and quality of life. Results: NHHD reduced systolic BP by 25 mmHg (p<0.001) with fewer antihypertensives. Phosphate control improved, with 70% discontinuing binders. Left ventricular mass decreased by 15%. Quality of life scores significantly improved. Discussion: Barriers include patient training, caregiver burden, and nocturnal vascular access issues. Conclusion: NHHD provides superior clinical outcomes but requires adequate resources.