Focus and Scope

Advances in Dermatology, published by Academic Press Inc. collaborates with American Medical Association. are dedicated to providing physicians with the best research and important information in the world of medical research and science and to present the information in a format that is understandable and clinically useful. Committed to publishing multidisciplinary research that spans the entire spectrum of healthcare and medicine access, Advances in Dermatology aims at an international audience of pharmacists, clinicians, medical ethicists, regulators, and researchers, providing an online forum for the rapid dissemination of recent research and perspectives in this area.

Advances in Dermatology Evidence seeks to advance clinical trial research and clinical practice by:

• Publishing high-quality studies from the front lines of medical research.
• Challenging the medical community to take new approaches to clinical trial design and execution that yield more powerful clinical evidence.
• Sparking debate and conversation around areas of medicine where clinical decisions are made without sufficient evidence.
• Engaging physicians in a more sophisticated and meaningful way with clinical evidence.

Adhering to the rigorous peer-review and quality standards expected from Advances in Dermatology Evidence publishes:

• Original research, clinical trials, and other clinically grounded work (e.g., epidemiology studies, first-in-human trials, meta-analyses) that validate or challenge prior clinical findings.
• Standard reviews, systematic reviews, and other review types that contextualize research findings with the aim of accelerating clinical adoption of new evidence.
• Case studies and reviews of clinical trial methodology that enhance understanding of trial strengths and weaknesses.
• Curbside consult series that addresses common patient care issues.
• Morning Report series solicited case presentation articles that are delivered in a morning report format.

Generation of Evidence

The process of generating evidence is a key area of focus for Advances in Dermatology Evidence. We encourage readers to evaluate the reasoning behind the complex decisions that investigators make in trial design and execution, and to assess the quality of evidence produced in trials. Our goal is to build a community that takes a rigorous approach to evaluating evidence and assessing its impact on clinical decision-making.

Statistical Methods

Advances in Dermatology Evidence guides readers toward a deeper understanding of the statistical methods used in trials. We provide concise, digestible explanations of research methods to inform the interpretation of the resulting data. In addition, we introduce readers to emerging statistical methods and types of data that will play an increasingly prominent role in future trials.

Multidisciplinary Coverage

Advances in Dermatology Evidence publishes content relevant across all medical disciplines to advance the discussion of how to generate evidence that informs patient care. Physician-scientists, trialists, and general medicine and subspecialty clinicians will all benefit from this publication.

Advances in Dermatology covers themes including, but not limited to:

1. Medical and Clinical Dermatology

• Inflammatory Dermatoses:
• Psoriasis and Psoriatic Arthritis: Pathophysiology, biologics, and novel small molecule therapies.
• Atopic Dermatitis (Eczema): Skin barrier dysfunction, immunology, and advanced therapeutics.
• Rosacea, Seborrheic Dermatitis, and Lichen Planus.
• Autoimmune, Connective Tissue, and Bullous Diseases:
• Cutaneous Lupus Erythematosus, Dermatomyositis, and Scleroderma.
• Blistering Diseases: Pemphigus vulgaris, Bullous Pemphigoid, and Dermatitis Herpetiformis.
• Vasculitis and other systemic diseases with skin manifestations.
• Infectious Dermatology:
• Bacterial Infections: Impetigo, cellulitis, folliculitis, MRSA infections.
• Fungal Infections (Mycology): Dermatophytosis (tinea), candidiasis, deep fungal infections.
• Viral Infections: Herpes simplex (HSV), varicella-zoster (VZV), human papillomavirus (warts), molluscum contagiosum.
• Disorders of the Hair and Nails (Trichology):
• Alopecias: Androgenetic alopecia, alopecia areata, telogen effluvium, scarring alopecias.
• Hirsutism and hypertrichosis.
• Nail disorders: onychomycosis, nail psoriasis, tumors of the nail unit.
• Acne, Rosacea, and Hidradenitis Suppurativa:
• Pathophysiology and management of acne vulgaris.
• Advanced therapies for hidradenitis suppurativa.
• Disorders of Pigmentation:
• Vitiligo: Pathogenesis and repigmentation therapies.
• Melasma and post-inflammatory hyperpigmentation.
• Severe Cutaneous Adverse Reactions (SCARs) and Drug Eruptions:
• Stevens-Johnson Syndrome / Toxic Epidermal Necrolysis (SJS/TEN).
• Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS).
• Genodermatoses:
• Inherited disorders of keratinization (e.g., Ichthyosis) and skin fragility (e.g., Epidermolysis Bullosa).

1. Dermatologic Surgery and Oncology

• Skin Cancer (Dermato-Oncology):
• Melanoma: Early diagnosis (dermoscopy), surgical management, sentinel lymph node biopsy, adjuvant and systemic therapies (immunotherapy, targeted therapy).
• Non-Melanoma Skin Cancer (NMSC): Basal Cell Carcinoma (BCC) and Squamous Cell Carcinoma (SCC).
• Rare Cutaneous Malignancies: Merkel Cell Carcinoma, Dermatofibrosarcoma Protuberans (DFSP), Sebaceous Carcinoma.
• Cutaneous Lymphoma (e.g., Mycosis Fungoides).
• Surgical Procedures and Techniques:
• Mohs Micrographic Surgery: Techniques, indications, and outcomes.
• Standard surgical excision, flaps, and grafts for reconstruction, particularly on the face, head, and neck.
• Procedural Dermatology:
• Cryosurgery, electrosurgery, and curettage.
• Laser surgery for benign and pre-malignant lesions (e.g., actinic keratoses).

1. Aesthetic and Cosmetic Dermatology / Medicine

• Injectables:
• Neuromodulators: Botulinum toxin for aesthetic (e.g., wrinkles) and medical (e.g., hyperhidrosis) uses.
• Soft Tissue Fillers: Hyaluronic acid, calcium hydroxylapatite, poly-L-lactic acid for facial rejuvenation, volumization, and contouring.
• Energy-Based Devices:
• Lasers: Ablative and non-ablative fractional lasers for skin resurfacing, pigment-specific lasers for tattoos and pigmented lesions, and vascular lasers for telangiectasias and port-wine stains.
• Intense Pulsed Light (IPL): For photorejuvenation.
• Radiofrequency (RF) and Ultrasound (HIFU/MFU) Devices: For skin tightening and non-invasive lifting.
• Body Contouring and Fat Reduction:
• Non-invasive technologies like cryolipolysis, radiofrequency, and laser lipolysis.
• Cosmeceuticals and Skin Care Science:
• Clinical evidence for topical agents like retinoids, antioxidants, peptides, and sunscreens.
• Superficial Rejuvenation Procedures:
• Chemical peels (superficial to medium depth).
• Microneedling and dermabrasion.
• Sclerotherapy and Laser Treatment of Leg Veins.

1. Specialized Areas in Dermatology

• Dermatopathology:
• Microscopic diagnosis of skin diseases.
• Clinicopathologic correlation.
• Advanced diagnostic techniques: immunofluorescence, immunohistochemistry, and molecular pathology.
• Venereology (Sexually Transmitted Infections - STIs):
• Cutaneous manifestations of syphilis, gonorrhea, chlamydia.
• Diagnosis and management of genital warts (HPV) and genital herpes (HSV).
• Dermatologic manifestations of HIV/AIDS.
• Pediatric Dermatology:
• Management of common pediatric conditions (atopic dermatitis, acne, warts).
• Vascular anomalies (hemangiomas, vascular malformations), nevi, and other birthmarks.
• Contact and Occupational Dermatitis:
• Patch testing for allergic contact dermatitis.
• Management of irritant and allergic occupational skin diseases.
• Photodermatology and Photobiology:
• Diagnosis and management of photosensitivity disorders (e.g., porphyrias, polymorphic light eruption).
• Phototherapy (Narrowband UVB, PUVA) for skin diseases like psoriasis and vitiligo.

1. Foundational Science and Cross-Cutting Themes

• Cutaneous Biology and Immunology:
• Basic science research on skin barrier function, wound healing, skin aging, melanocyte biology, and skin immunology.
• Translational Research:
• "Bench-to-bedside" studies translating basic science discoveries into new diagnostic tools and therapies.
• Advanced Diagnostics and Technology:
• Non-invasive imaging: Dermoscopy, reflectance confocal microscopy, and optical coherence tomography (OCT).
• Artificial Intelligence (AI) and machine learning for diagnostic imaging analysis.
• Public Health and Epidemiology:
• Epidemiology of skin cancer and other skin diseases.
• Sun protection campaigns and public health policies related to skin health and STIs.
• Ethics and Patient Safety:
• Ethical considerations in cosmetic procedures and clinical trials.
• Patient safety protocols in procedural dermatology.